Dr. Minghui Zhang

Director, Cell Therapy Research Laboratory, Tsinghua University School of Medicine; Founder, Beijing Lehe New Medical Clinic

Key Roles

  • Director. Innovative Medicine Special Fund, China Scholarship Development Foundation.
  • Immune Cell Therapy Innovator
  • Published landmark cover study in Nature Immunology (2004), revealing immune microenvironment’s role in reversing dendritic cell dysfunction.
  • Discovered CD8+vNKT cells (2002), a unique immune subpopulation with bidirectional anti-tumor effects.

Clinical Breakthroughs

  • Developed vNKT cell therapy for advanced solid tumors:
  • 80%+ 5-year tumor-free rate in Stage III patients.
  • 40%+ 5-year tumor-free rate in Stage IV colorectal cancer with metastasis (combined with minimally invasive surgery).

Chronic Disease Innovations

  • Non-Chemical Therapies
  • Leveraged mesenchymal stem cells (MSCs) and gut microbiota modulation to treat
  • Type 2 diabetes, Hashimoto’s thyroiditis, inflammatory bowel disease (IBD).
  • Alzheimer’s disease, stroke sequelae (achieving functional reversal in some cases).
  • Founder : Established Lehe New Medical Chronic Disease Rehabilitation Center integrating research, diagnosis, and holistic care for chronic conditions.

Academic & Clinical Impact

  • Bridged foundational immunology with translational applications, redefining standards in oncology and chronic disease management.
  • Global leader in advancing precision immune therapies and regenerative medicine.